Hydroxyapatite and Other Calcium Orthophosphates :
Nanodimensional, Multiphasic and Amorphous Formulations
Nanodimensional, Multiphasic and Amorphous Formulations[/b]
by Sergey V. Dorozhkin
English | 2017 | ISBN: 1536119024 | 333 Pages | PDF | 6.87 MB
As the inorganic constituents of skeletons, dentine and the enamel of teeth in all vertebrates, as well as antlers of male deer, calcium orthophosphates (CaPO 4 ) appear to be the key materials to sustain all life on Earth. Therefore, biologically relevant CaPO 4 possess all the necessary features of the biomaterials, such as biocompatibility, bioactivity, bioresorbability, osteoconductivity, osteoinductivity, and appear to be non-toxic, non-inflammatory and non-immunogenic. In this book, the author presents current state-of-the-art applications on three popular types of CaPO 4 : nano-scaled (nano-dimensional), multiphasic (polyphasic) and amorphous CaPO 4 . Topics discussed include the preparation, structure, composition, properties and biomedical applications of these types of CaPO 4 combined with the specific information for each type. Namely, occurrence in the calcified tissue of mammals is discussed for both nano-scaled and amorphous types of CaPO 4 ; both known and potential formulations, as well as their stability are discussed for multiphasic CaPO 4 , while both the morphology and the available knowledge on amorphous-to-crystalline transformations are discussed for amorphous CaPO 4.
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