Applied Biocatalysis in Specialty Chemicals and Pharmaceuticals By Badal C. Saha and David C. Demirjian (Eds.)
2001 | 294 Pages | ISBN: 0841236798 | PDF | 34 MB
Content: Machine generated contents note: Overview -- 1. Advances in Enzyme Development and Applied Industrial -- Biocatalysis2 -- Badal C. Saha and David C. Demirjian -- Biocatalyst Discovery, Characterization, and Engineering -- 2. Selected Historical Perspectives in Biocatalysis, 1752-1960 14 -- S.L. Neidleman -- 3. Screening of Hydrolase Libraries Using pH-Shift Reagents: -- Rapid Evaluation of Enantioselectivity 41 -- Francisco Moris-Varas, Laura Hartman, Amit Shah, -- and David C. Demirjian -- 4. Selection of Saprophytic Bacteria and Characterization of Their -- Fatty Acid Bioconversions during Compost Formation 55 -- T.M. Kuo and T. Kaneshiro -- 5. D-Phenylalanine Biosynthesis Using Escherichia Coli: Creation -- of a New Metabolic Pathway65 -- Paul P. Taylor, Nigel J. Grinter, Shelly L. McCarthy, -- David P. Pantaleone, Jennifer L. Ton, Roberta KfYoshida, -- and Ian G. Fotheringham -- 6. Improvement of Enzyme Character by Gene Shuffling 76 -- Kiyoshi Hayashi, Qin Wang, Satoru Nirasawa, -- Tsuyoshi Simonishi, Motomitsu Kitaoka, and -- 7. Bioconversion of Unsaturated Fatty Acids to Value-Added -- Products 92 -- Ching T. Hou -- 8. The Nicotinamide Cofactors: Applications in Biotechnology 103 -- Hugh O'Neill and Jonathan Woodward -- 9. Production of Galacto-Oligosaccharides from Lactose by -- Immobilized fi-Galactosidase 131 -- Shang-Tian Yang and Julia A. Bednarcik -- 10. Phyllosilicate Sol-Gel Immobilized Enzymes: Their Use as -- Packed Bed Column Bioreactors 55 -- A.F. Hsu, T.A. Foglia, K. Jones, and S. Shen -- 11. Biocatalytic Preparation of D-Amino Acids 165 -- David P. Pantaleone, Paul P. Taylor, Tamara D. Dukes, -- Kurt R. Vogler, Jennifer L. Ton, Daniel R. Beacom, -- Shelly L. McCarthy, Bruce E. Meincke, L. Kirk Behrendt, -- Richard F. Senkpeil, and Ian G. Fotheringham -- Applications: Pharmaceutical -- 12. Application of Biocatalysis in Chemical Process Development: -- A Few Case Studies 178 -- Weiguo Liu -- 13. Method for the Stereoselective Production of Chiral Vicinal -- Aminoalcohols: Establishing Two Chiral Centers by -- Diastereoselective Reduction 191 -- J. David Rozzell -- 14. Stereoselectivity of Penicillin Acylase Catalyzed Ester -- Hydrolysis 200 -- Ravindra S. Topgi -- 15. Synthesis of Chiral Pharmaceutical Intermediates by -- Oxidoreductases 216 -- Ramesh N. Patel and Ronald L. Hanson -- 16. Production of Chiral Amines with w-Transaminase 248 -- Jong-Shik Shin and Byung-Gee Kim -- 17. Enantiorecognition of Chiral Acids by Candida rugosa Lipase: -- Two Substrate Binding Modes Evidenced in an Organic -- Medium263 -- Per Berglund, Maria Christiernin, and Erik Hedenstrom -- Author Index275 -- Subject Index276.
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