Glycosignals in Cancer: Mechanisms of Malignant Phenotypes
Springer | Biochemistry & Biophysics | February 27, 2016 | ISBN-10: 443155937X | 219 pages | pdf | 5.5 mb
Editors: Furukawa, Koichi, Fukuda, Minoru (Eds.)
Shows how sugar chains are critically involved in malignant phenotypes of cancers
Presents a variety of modes by which sugar chains modulate cell signals determining cell fates
Explains how up-to-date results of life technology and information are being applied in glycobiology research of cancers
Inspires the application of knowledge about signals generated via glycosylation for diagnosis and therapy of cancers
This book is a collection of cutting-edge studies on the functions and mechanisms of glycosylation in cancers. Along with progress in genomics and proteomics, new findings in the significance of these complex carbohydrates, through the regulation of cell signals, have been elucidated in a wide variety of biological events. This volume provides a comprehensive summary of glycosignals and their involvement in cancer, covering numerous topics such as glycosylation machineries, regulation of phenotypes, cell signaling, immune regulation, complex carbohydrate organization, and clinical applications. The contents have been organized to promote ready understanding, covering basic to clinical research and studies on micromolecules, to animal/human cells and tissues. This book is an essential read for students and young researchers interested in cancers and carbohydrates. Specialists in glycobiology will also benefit from the new results and approaches detailed here, which provide insights into future directions of functional studies of sugar chains in both basic and applied research.
Number of Illustrations and Tables
24 illus., 10 in colour
Topics
Biochemistry
Cancer Research
Cell Biology
Oncology
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